Gingeren™

Menstrual health and sexual wellness

Comfort from
the first cycle.

“Efficacy of a Standardized Ginger Extract for Menstrual Pain and Associated Symptoms in Women With Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Trial.”Published · Cureus, 2026

“A Standardized Ginger Extract Improves Sexual Function and Sexual Quality of Life in Women with Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Trial.”Published · Genetics and Molecular Research, 2026

Study design.

Design
Randomised, double-blind, placebo-controlled, multicentre trial
Participants
100 women aged 20 to 30 with moderate primary dysmenorrhoea (VAS 4 to 6)
Intervention
Gingeren™ at 200 mg a day, or placebo, through three menstrual cycles, after two baseline cycles
Measured
Primary: menstrual pain on the VAS and dysmenorrhoea severity on the WaLIDD score. Secondary: menstrual distress (MEDI-Q), menstrual blood flow, sexual function (FSFI), sexual quality of life and general wellness. Exploratory: the PGF2α biomarker, the vaginal microbiome and estrogen levels

Key outcomes.

Menstrual comfortPain, its days and its intensity, and the biomarker behind it
68%Reduction in WaLIDD score
74%Better working ability during the cycle
64%Reduction in days of pain (WaLIDD)
44%Reduction in menstrual blood flow
34%Reduction in pain score (VAS)
57%Reduction in menstrual distress (MEDI‑Q)
17%Lower PGF2α, the prostaglandin behind uterine contractions
Sexual wellbeingFunction and quality of life
51.6%Better sexual function on FSFI
47%Better sexual quality of life
General wellnessDigestion and cold symptoms
64%Better digestive health
56%Reduction in gastric discomfort
38%Reduction in cold symptoms

The results.

Dysmenorrhoea severityWaLIDD total: working ability, location, intensity and days of pain; lower is better
Dysmenorrhoea severity on the WaLIDD score (working ability, location, intensity, days of pain)12345678C1C2BaseC3C4C5WaLIDD total score************
PlaceboGingeren™ 200 mg/day

Lower from the first cycle. ****p < 0.0001 vs placebo.

Menstrual painVisual analogue scale, 0 to 10; lower is better
Menstrual pain on the visual analogue scale, two cycles before dosing and three on Gingeren3.03.54.04.55.05.56.0C1C2BaseC3C4C5VAS pain score************
PlaceboGingeren™ 200 mg/day

Lower from the first cycle. *p < 0.05, ****p < 0.0001 vs placebo.

PGF2αProstaglandin F2α in blood, pg/ml; lower is better
Prostaglandin F2 alpha in blood, by cycle180190200210220230240BaseC3C4C5PGF2α, pg/ml**********
PlaceboGingeren™ 200 mg/day

Lower each cycle, while placebo rose. **p < 0.01, ****p < 0.0001 vs placebo.

Digestive healthGeneral wellness questionnaire; higher is better
Digestive health on the general wellness questionnaire, by cycle2.02.53.03.54.04.55.0BaseC3C4C5Digestive health score*********
PlaceboGingeren™ 200 mg/day

Improved with regular consumption, while placebo declined. ***p < 0.001 vs placebo.

Sexual functionFemale Sexual Function Index, total; higher is better
Female Sexual Function Index, total score101520253035C1C2BaseC3C4C5FSFI total score********
PlaceboGingeren™ 200 mg/day

Across all six domains: desire, arousal, lubrication, orgasm, satisfaction and comfort. ****p < 0.0001.

Also measured.

The vaginal microbiome and estrogen levels stayed unchanged.

No clinically meaningful safety concerns: safe for use.

The publication.

“Efficacy of a Standardized Ginger Extract for Menstrual Pain and Associated Symptoms in Women With Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Trial.” Cureus, 2026.

“A Standardized Ginger Extract Improves Sexual Function and Sexual Quality of Life in Women With Primary Dysmenorrhea: A Randomized, Double-Blind, Placebo-Controlled Trial.” Genetics and Molecular Research, 2026.

Full texts available on request.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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