Branded actives Xanthogreen®

Fast actinglutein esters.

Clinically proven for faster deposition of lutein on the macula.

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  • 42.54%Macular pigment optical density
  • Day 30Significant lutein deposition on the macula
  • 20%Lutein equivalent
A woman and her elderly mother reading a book together on the sofa

Why Xanthogreen

Free lutein takes months
to deposit on the macula.

Lutein is a naturally occurring carotenoid concentrated in the macula, where it plays an important role in supporting visual health. Xanthogreen® takes a more advanced approach, delivering lutein in esterified form, in a shorter time.

  1. 01

    Solvent free

    Extracted with a patented supercritical fluid extraction (SCF-CO2) process.

  2. 02

    Stability

    Lutein esters, naturally present in marigold flowers, are the most stable form.

  3. 03

    Grades

    Xanthogreen® is available in three grades, each clinically studied.

  4. 04

    Fast onset

    Macular pigment rose significantly against placebo from day 30.

The approach

Three grades for
different formats.

It disperses the lutein esters in a homogenous oil: stable, solvent-free, and broken into a nanoemulsion in the gut for better absorption.

Day 0Day 15Day 30Day 60Day 90
Xanthogreen® TOS · +42.54%Xanthogreen® · +31.96%Xanthogreen® ULTRA · +29.88%
Macular pigment optical density, change from baseline. Significant from day 30 on all three grades; ULTRA at half the lutein dose.
  1. 01
    A true oil solution

    Breaks into a nanoemulsion in the gut, for better absorption.

  2. 02
    The lymphatic route

    Lutein esters are absorbed mainly through the lymphatic system, avoiding first-pass metabolism (degradation in the liver).

  3. 03
    4 weeks

    Measurable lutein reaches the retina.

Xanthogreen®

Standardization: lutein ester 20%

Dose200 mg

Xanthogreen® TOS

True oil solution of lutein ester 10%

A homogenous single-phase, clean oil solution in a lipid matrix, for softgels. The strongest response in the study.

Dose400 mg

Xanthogreen® ULTRA

Standardization: lutein ester 15%

A true oil solution converted into a nano-emulsion, for ready absorption and action in the body.

Dose134 mg

Patented process for lutein extractionAvailable as oil and powderContract farming and traceability

The evidence

Macular pigment optical density
up from day 30.

One human study, to be published soon: how fast lutein from Xanthogreen® reached the macula.

Clinical study · To be published

Macular pigment optical density up from day 30.

128 adults · aged 18–50 · 3 grades · 90 days · vs placeboTo be published soon

Macular pigment optical densitySignificant improvement in MPOD levels from baseline
42.54%Xanthogreen® TOS
31.96%Xanthogreen®
29.88%Xanthogreen® ULTRA
Contrast sensitivityImprovement from baseline at day 90
52.2%Xanthogreen® TOS
52.4%Xanthogreen®
48.9%Xanthogreen® ULTRA
At 0.25°Macular pigment optical density; higher is better
Macular pigment optical density at 0.25 degrees over 90 days, placebo and the three Xanthogreen grades0.200.240.280.320.360.40BaselineDay 15Day 30Day 60Day 90MPOD*********
PlaceboXanthogreen®Xanthogreen® TOSXanthogreen® ULTRA

Significant from day 30 on all three grades. *p < 0.0001 vs placebo; TOS ahead of both other grades, p < 0.0001.

Read the full study
The same mother and daughter laughing together on the sofa

What the study found

A rise in macular pigment
optical density over 90 days.

In healthy adults, for all three grades of Xanthogreen®.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Marigold flowers

Know your ingredient

Xanthogreen®

Tagetes erecta, the marigold, whose petals are one of the richest sources of lutein, a naturally occurring carotenoid important for eye health and vision. Efficient delivery and absorption of lutein is the key. Xanthogreen® is the result of a sophisticated lutein delivery system, designed to help build macular lutein levels efficiently: advanced science brought closer to the benefits your eyes need, without compromising on purity and quality.

  1. StableLutein esters

    Naturally occurring in the source.

  2. HomogenousOil dispersion

    Better lymphatic uptake.

  3. CleanProduct

    Solvent-free.

Healthy eyes and clearer vision, supported faster by a specialty lutein.

Formulation

How it’s made.

Lutein esters from marigold flowers, extracted solvent-free with a patented SCF-CO2 process and formulated with BioRelay™ true oil solution, in three grades: Xanthogreen® 20% (oil or powder), TOS 10% (oil) and ULTRA 15% (oil).

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Botanical
Tagetes erecta, marigold flower
Key actives
Lutein esters
Standardization
Xanthogreen®: lutein ester 20% · Xanthogreen® TOS: lutein ester 10% · Xanthogreen® ULTRA: lutein ester 15%
Technology
BioRelay™ true oil solution, powered by SCEMOD™
Grades
Xanthogreen® 20% · Xanthogreen® TOS 10% · Xanthogreen® ULTRA 15%
Forms
Xanthogreen®: oil, powder · Xanthogreen® TOS: oil · Xanthogreen® ULTRA: oil
Dose
Xanthogreen®: 200 mg · Xanthogreen® TOS: 400 mg · Xanthogreen® ULTRA: 134 mg
Certification
Halal · Kosher
Positioning
Eye health

Certification

Application formats

SoftgelsCapsulesGummies

Xanthogreen® for capsules and softgels · Xanthogreen® TOS for softgels · Xanthogreen® ULTRA for softgels and gummies

The daughter at the table by the window, taking a softgel with water

Also from Ennature

Next step

Working with Xanthogreen®?

Tell us the format and the market, and we will send a sample with its specification.

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Download the Xanthogreen® brochure

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