Maxicuma®

Pharmacokinetic study

Higher uptake
of curcuminoids.

“Bioavailability Study of Maxicuma Capsules Versus Micronized Curcumin Capsules as A Single Oral Dose in Fasted Healthy Adult Human Subjects.”Published · Current Research in Complementary & Alternative Medicine 7:191 (2023)

Study design.

Design
Crossover comparative pharmacokinetic study
Participants
14 healthy adults
Intervention
Maxicuma® and micronized curcumin extract 95%, at an equal dose
Measured
The total curcuminoid profile in the blood: time to peak (Tmax), peak concentration (Cmax) and total exposure (AUC)

Key outcomes.

Pharmacokinetic outcomesAgainst micronized curcumin extract 95%, at an equal dose
1.6×Higher Tmax
2.4×Higher Cmax
3×Higher AUC
172×More free curcumin

The results.

Comparative pharmacokinetic profileFree curcuminoids in plasma, total exposure (AUCt)
Free curcuminoids in plasma, total exposure: Maxicuma against micronized curcumin 95%05001,0001,5002,0002,5003,000AUCt, ng·h/mL2,690861Free curcumin851267Free DMC8930Free BDMC
Maxicuma®Micronized curcumin 95%

Maxicuma® is more bioavailable than micronized curcumin extract 95%, at an equal dose.

The publication.

Rachchh M, Gokani R, Patel H, Khamar J, Patel A. “Bioavailability Study of Maxicuma Capsules Versus Micronized Curcumin Capsules as A Single Oral Dose in Fasted Healthy Adult Human Subjects.” Current Research in Complementary & Alternative Medicine 7:191 (2023).

doi:10.29011/2577-2201.100091

Full text available on request.

The other Maxicuma® study

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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